Tindamax (tinidazole) Protects Vaginal Lactobacilli

Within the vaginal ecosystem, balanced levels of lactobacilli, the protective bacteria that help to control disease-causing organisms, are vital to maintaining the homeostasis of vaginal flora.¹ When the normal concentration of lactobacilli is reduced by overgrowth of anaerobic bacteria such as Gardnerella vaginalis and Bacteroides spp., the characteristic symptoms of bacterial vaginosis develop.^2-4

Tinidazole therapy treats BV with proven efficacy while protecting lactobacilli

In treating BV, one of the goals of therapy is to target disease-causing pathogens while sparing lactobacilli, which are essential for the establishment of normal flora patterns.

This protective benefit also helps to reduce the risks of secondary vaginal candidiasis from BV treatment.

Tinidazole is associated with a low incidence of vaginal candidiasis (4.7%)
Less risk of secondary vaginal candidiasis infection enhances recovery and helps reduce patient return rate

Schwebke J. Understanding bacterial vaginosis: Diagnosis, treatment, and improved outcomes. J Family Prac. 2007;(suppl):1-8.
Sweet RL. Gynecologic conditions and bacterial vaginosis: implications for the non-pregnant patient. Infect Dis Obstet Gynecol. 2000;8(3-4):184-90.
Hillier SL, Krohn MA, Nugent RP, Gibbs RS. Characteristics of three vaginal flora patterns assessed by gram stain among pregnant women. Vaginal Infections and Prematurity Study Group. Am J Obstet Gynecol. 1992 Mar;166(3):938-44.
Hillier SL. Diagnostic microbiology of bacterial vaginosis. Am J Obstet Gynecol. 1993 Aug;169(2 Pt 2):455-9.